How Does Medication For ADHD Work? Stimulants are the most commonly prescribed ADHD medications. They work by increasing the levels of brain chemicals called dopamine and norepinephrine. They include the methylphenidate (Ritalin, Concerta), amphetamine, dextroamphetamine (Adderall) and lisdexafetamine (Vyvanse). Doctors often prescribe these in long-release forms that last for six
